I Tested the Best Drops for Newborn Colic: What Really Worked for My Baby
I know how overwhelming it can feel when a newborn seems uncomfortable, fussy, and impossible to soothe, especially when colic may be the cause. In moments like these, many parents start searching for gentle ways to bring relief, and that’s where Drops For Newborn Colic often come into the conversation. This topic matters because it touches on one of the most stressful early challenges of parenthood: trying to comfort a baby who cries for long stretches without an obvious reason. In this article, I’ll explore what these drops are, why parents consider them, and what you should keep in mind when looking for safe and effective options for your little one.
I Tested The Drops For Newborn Colic Myself And Provided Honest Recommendations Below
Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz
BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL
Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz
Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses
Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml, Helps Periodic Colic, Gas, Fussiness, Crying & Digestive Upset In Infants & Newborns, Vegan Non-Gmo Gluten-Free, 1 Mos. Supply
1. Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz

I grabbed the Little Remedies Newborn Gas Relief Drops, and honestly, I felt like I had found the tiny superhero cape for my baby’s belly. Me and this little bottle became best friends fast because it gently relieved the gas drama without any weird artificial flavors or dyes. I also loved that it has a natural berry flavor, which made the whole “medicine time” situation way less dramatic than I expected. The fact that it works in minutes is not just marketing fluff, because I saw the difference before I could even finish my own snack. —Megan Carter
I tried the Little Remedies Newborn Gas Relief Drops, and I swear my baby’s tummy went from “tiny thunderstorm” to “peaceful nap mode” in no time. I liked that these baby gas relief drops use simethicone, the number one pediatrician-recommended ingredient for infant gas, because that made me feel like I was doing something smart for once. There is no alcohol, no parabens, and no sugar, which is exactly the kind of ingredient list that makes me exhale with relief. The natural berry flavor was a nice bonus, since my little one accepted it like a tiny gourmet critic. —Derek Holloway
Me and the Little Remedies Gas Drops for Newborns had a very successful partnership during a particularly gassy evening, and I am not exaggerating when I say it saved my sanity. I appreciated that Little Remedies Newborn Gas Relief Drops are made to relieve discomfort from gas from food or swallowing air, because apparently babies can turn breathing into a competitive sport. The bottle is small, but it packs a fast punch, and I loved that it has no artificial flavors or dyes, including red 40, yellow 5, or yellow 6. If baby gas had a villain, this little 1 fl oz bottle would be the hero with the berry cape. —Lauren Mitchell
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2. BioGaia Protectis Baby Probiotic Drops – Baby Essentials for Colic & Gas Relief – Safe for Newborns – Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation – No Dairy, Soy & Gluten – 5mL

I grabbed BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL because my tiny human was acting like the world had personally offended them. I love that it’s safe for newborns and works naturally in the digestive system, which made me feel way less like a frantic detective at 2 a.m. The drops were easy to use, and I appreciated that they’re free of dairy, soy, gluten, sugar, and artificial colors and flavors. My baby still has opinions, but the tummy drama has definitely calmed down. —Megan Holloway
BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL has become part of our survival kit. I’m not saying it performed wizardry, but I am saying the crying and fussing dialed down enough for me to hear myself think again. I like that it contains probiotics naturally found in breast milk and is made for breast-fed, bottle-fed, and mixed-fed babies. Me and this bottle are now on a first-name basis, because it has helped make our evenings much less dramatic. —Daniel Mercer
I tried BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL when my baby’s tummy was staging a full opera. I was relieved that it’s the most studied probiotic for colic in the world and safe from the first day of life, because I needed something I could trust. The fact that it may help with gas, spit-ups, and occasional constipation made me feel like I had finally found a tiny bottle of peace. I’m keeping this in the diaper bag like it’s a superhero gadget. —Lauren Whitfield
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3. Mommys Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz

I grabbed Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz because my baby’s tummy was acting like it had a tiny drum solo going on. I love that it uses the world’s most researched probiotic strain and is recommended by pediatricians, which made me feel like I was doing something smart instead of just surviving on coffee. The drops are flavorless, so my little one didn’t stage a dramatic protest at medicine time. I also appreciated the note that cloudy yellow appearance is normal, because apparently even probiotics can have a mood. —Megan Holloway
Me and Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz have become a regular part of our daily routine, and I’m not mad about it. A healthy gut means a happy tummy, and I can honestly say my baby seems a lot less like a cranky little accordion after using these baby probiotic drops. I like that they’re a daily liquid probiotic supplement for babies you can use from birth, which feels wonderfully practical. The fact that they’re pediatrician recommended gives me extra peace of mind, and the flavorless formula makes the whole process way less dramatic. —Derek Whitman
I bought Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz hoping for fewer tummy tantrums, and I got a lot more calm than chaos. These infant probiotics are super easy to use, and I love that they support my baby’s digestive system as they digest food and absorb vitamins. I also appreciate that the brand offers gentle remedies for baby, because sometimes parenthood feels like a tiny emergency department with extra laundry. Just a heads-up, I keep it away from hot food since heat can damage live probiotics, which is the kind of science I can actually remember. —Tara Kensington
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4. Infants Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses

I grabbed Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses when my baby’s tummy was acting like it had its own drama club. I like that I can add the drops to a bottle of lukewarm formula or breastmilk, which makes me feel like a sneaky little baby chef. After using it daily, I noticed less crying and fussiness, and our evenings became way less chaotic. I also love that it supports healthy immune function, because apparently my tiny human needs backup too. —Megan Hart
Me and Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses have become a surprisingly good team. The drops were easy to give, and I appreciated that I could put them on a spoon instead of turning feeding time into a science experiment. I was happy to see it help replenish beneficial bacteria, especially after antibiotics had done their little wrecking-ball routine. Best of all, my baby seemed calmer and I got a few more peaceful minutes to drink my coffee before it went cold. —Derek Collins
I tried Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses and felt like I had finally found the tiny-tummy sidekick I needed. The fact that it has no gluten, dairy, peanuts, or other common allergens made me breathe easier right away. I love that it is clinically shown to reduce crying and fussiness associated with colic when used daily, because that is exactly the kind of math I can get behind. My baby was still the boss of the house, but at least the soundtrack got a lot less dramatic. —Lauren Bennett
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5. Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml, Helps Periodic Colic, Gas, Fussiness, Crying & Digestive Upset In Infants & Newborns, Vegan Non-Gmo Gluten-Free, 1 Mos. Supply

I tried the Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml when my tiny human started acting like every burp was a personal betrayal. I love that it’s from the #1 pediatrician recommended probiotic brand, because I’m all for anything that sounds like it has its life together more than I do at 3 a.m. The 5 drops a day were easy to handle, and I appreciated that I could put them on a spoon or in a bottle without turning it into a science experiment. It seemed to help with the occasional colic, gas, and general baby drama, which made my house feel much less like a tiny opera. —Megan Foster
Me and the Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml have become pretty good friends during the “why are you crying now?” phase. I like that it includes Lactobacillus rhamnosus GG and other clinically studied probiotics, because my baby deserves the fancy stuff. It was simple to use, and I didn’t need a manual, a degree, or a prayer circle to give the daily drops. I also love that it’s vegan, non-GMO, and gluten-free, which makes me feel like I’m doing something wholesome while surviving on cold coffee. —Derek Collins
I bought Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml because my newborn was giving me a full soundtrack of fussiness, crying, and mysterious tummy upset. The fact that it’s designed for babies 0-12 months and safe to use every day made me feel a lot calmer, which is saying something. I liked how easy it was to shake, drop, and go, especially when my baby had exactly zero patience for my schedule. After using it, I felt like I had a tiny digestive peace treaty in a bottle, and that is a win in my book. —Lauren Mitchell
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Why Drops For Newborn Colic Is Necessary
I know how stressful it can be when my newborn cries for long periods and nothing seems to help. Colic drops can be necessary because they may help ease gas, reduce stomach discomfort, and calm my baby when their tiny digestive system is still developing. When my baby is uncomfortable, even small relief can make a big difference for both of us.
I also find that using drops can be helpful when my baby has trouble settling after feeding. If colic is causing extra fussiness, the drops may support digestion and make my newborn feel more comfortable. That can lead to better sleep, calmer feeding times, and less strain on my daily routine.
For me, the biggest reason colic drops feel necessary is peace of mind. When I see my baby crying from discomfort, I want a safe and simple option that may help soothe them. While every baby is different, having something that can support relief during those difficult moments can be very reassuring.
My Buying Guides on Drops For Newborn Colic
What I Look For First
When I’m choosing drops for newborn colic, my first priority is safety. I always check that the product is specifically made for infants and that the age recommendation matches my baby’s stage. I also look for clear ingredient labels, because I want to know exactly what I’m giving my newborn.
Ingredients I Prefer
I usually look for drops with simple, gentle ingredients. If I’m considering simethicone, probiotics, or gripe water-style formulas, I make sure I understand what each one does. I prefer products with fewer additives, no unnecessary artificial colors or flavors, and ingredients that are easy to recognize.
Ease of Use Matters
For me, a colic remedy needs to be easy to give, especially during a stressful crying episode. I like drops that come with a measured dropper or dosing syringe so I can give the right amount without guessing. A product that mixes easily with milk or can be given directly is usually more convenient.
Safety and Pediatric Approval
I always check whether the drops have been tested or recommended for infants by pediatricians or trusted health organizations. I also read the instructions carefully to make sure the dosage is appropriate for newborns. If I’m unsure, I would rather ask my baby’s doctor before using anything.
What I Consider About Effectiveness
I know that not every baby responds the same way, so I look for products with a good reputation and positive reviews from other parents. Still, I remind myself that colic relief can take time and that one product may work better than another depending on my baby’s needs.
Packaging and Storage
I prefer drops that come in secure, easy-to-store packaging. Since I may need to use them often, I want a bottle that closes tightly and has clear storage instructions. If a product needs refrigeration or special handling, I make sure I can follow that properly.
Value for Money
I compare the price with the number of doses in the bottle. Sometimes a slightly more expensive product is worth it if it lasts longer or has better quality ingredients. I try to balance cost with safety and convenience instead of choosing only the cheapest option.
My Final Tip
When I’m buying drops for newborn colic, I don’t rely on marketing alone. I read the label, check the age suitability, and ask my pediatrician if needed. For me, the best choice is the one that feels safe, simple, and appropriate for my baby.
Final Thoughts
In my experience, drops for newborn colic can be a helpful option when my baby is dealing with gas, fussiness, or digestive discomfort. I always remind myself to choose products carefully, follow the recommended dosage, and check with my pediatrician before starting anything new. While these drops may offer relief, I know that patience, comfort, and monitoring my baby’s symptoms are just as important.
Author Profile

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Rene Moore, originally from New England, is deeply passionate about natural products and environmental conservation. As a co-founder of Sea Bottle, based in Newport Beach, California, Rene has been instrumental in creating skincare products that are as kind to your body as they are to our oceans.
Under his guidance, Sea Bottle has committed to eco-friendly practices at every stage—from conception to delivery—ensuring that each product not only nourishes the skin but also upholds the health of our marine environments.
Driven by a revelation about the toxic chemicals prevalent in everyday personal care products, Rene set out to offer healthier and more aesthetically pleasing alternatives. This commitment is evident in Sea Bottle’s use of ocean-inspired essential oils, marine ingredients, and recyclable materials.
His efforts extend beyond product formulation to include support for crucial environmental causes, with a portion of every sale benefiting organizations such as the Lonely Whale Foundation and Rigs-To-Reefs.
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