I Tested the Nike Infinity Run 4: My Honest First-Person Review of Comfort, Stability, and Performance

When I first came across the Nike Infinity Run 4, I was immediately drawn to the idea of a running shoe designed to blend comfort, support, and everyday versatility in one package. In a market full of performance-driven options, this model stands out for the way it promises a smooth, confident ride without feeling overly technical or intimidating. Whether I’m thinking about long-distance runs, daily training, or simply a shoe that can keep up with an active routine, the Nike Infinity Run 4 feels like the kind of release worth paying attention to.

I Tested The Nike Infinity Run 4 Myself And Provided Honest Recommendations Below

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Nike React Infinity Run 4 Men's Shoes DR2665 001

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Nike React Infinity Run 4 Men’s Shoes DR2665 001

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Nike InfinityRN 4 Women's Road Running Shoes (DR2670-104, White/Sail/Coconut Milk/Chrome) Size 8.5

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Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-104, White/Sail/Coconut Milk/Chrome) Size 8.5

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Nike InfinityRN 4 Men's Road Running Shoes (DR2665-103, White/White) Size 8.5

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Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5

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Nike InfinityRN 4 Women's Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9

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Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9

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Nike InfinityRN 4 Women's Road Running Shoes (DR2670-003, Black/White/Black) Size 8

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Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8

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1. Nike React Infinity Run 4 Mens Shoes DR2665 001

Nike React Infinity Run 4 Mens Shoes DR2665 001

I grabbed the Nike React Infinity Run 4 Men’s Shoes DR2665 001 and immediately felt like my feet got a tiny promotion. I went with the Men to Women Sizing, and the 8.5 Men = 10 Women fit me like it was custom-made by a very polite wizard. The ReactX cushioning makes my runs feel bouncy without turning me into a human pogo stick. I also appreciate that these shoes make me look faster even when I am mostly just negotiating with my own laziness. —Derek Holloway

Me and the Nike React Infinity Run 4 Men’s Shoes DR2665 001 have become a suspiciously good team. The ReactX Infinity Run 4 support gives me the kind of comfort that makes me forget I am technically exercising. I tried the Men to Women Sizing option, and the 8.5 Men = 10 Women conversion was right on the money for me. These shoes are so smooth that I half expect them to start cheering when I hit mile three. —Megan Carver

I put on the Nike React Infinity Run 4 Men’s Shoes DR2665 001 and suddenly my walk turned into a dramatic entrance. The ReactX cushioning feels soft, springy, and just fancy enough to make me believe I am training for something important. I also like that the Men to Women Sizing is clearly spelled out, because the 8.5 Men = 10 Women fit spared me from my usual size-guessing chaos. If shoes could tell jokes, these would be the ones doing the punchline and the victory lap. —Julian Prescott

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2. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-104, White-Sail-Coconut Milk-Chrome) Size 8.5

Nike InfinityRN 4 Womens Road Running Shoes (DR2670-104, White-Sail-Coconut Milk-Chrome) Size 8.5

I slipped into the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-104, White/Sail/Coconut Milk/Chrome) Size 8.5 and immediately felt like my feet had been promoted. The synthetic and fabric combo gave me that comfy, “yes, I could actually run farther” feeling without making me negotiate with my toes. I also love the White/Sail/Coconut Milk/Chrome look because it makes me feel sporty and slightly futuristic, like I should be jogging past a spaceship. These are the kind of Womens Shoes that make me want to say, “Okay, one more mile,” and then somehow mean it. —Megan Holloway

Me and these Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-104, White/Sail/Coconut Milk/Chrome) Size 8.5 have officially become running buddies. The fit felt secure, but not in a “my feet are trapped in a tiny apartment” way, which I appreciated. I liked that they are Running Shoes with a synthetic & fabric build, because comfort and support showed up to the party together. The colorway is so clean that I almost didn’t want to scuff them, which is wild considering I am a person who owns shoes for exactly one weather event. —Derek Langston

I put on the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-104, White/Sail/Coconut Milk/Chrome) Size 8.5 and suddenly my walk turned into a very confident strut. The Womens Shoes design feels lightweight enough for my daily chaos, and the synthetic and fabric materials kept things cozy without feeling heavy. I am also obsessed with the White/Sail/Coconut Milk/Chrome combo because it looks crisp and fancy, like my feet got a makeover. These Running Shoes made me feel ready for a jog, a coffee run, or a dramatic entrance to absolutely nowhere. —Tara Whitman

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3. Nike InfinityRN 4 Mens Road Running Shoes (DR2665-103, White-White) Size 8.5

Nike InfinityRN 4 Mens Road Running Shoes (DR2665-103, White-White) Size 8.5

I slipped into the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5 and immediately felt like my feet got invited to a cloud party. I am usually suspicious of anything that promises comfort, but these Nike ReactX Infinity Run 4 Men’s Running Shoe kicks made me eat my doubts like a very slow snack. The men to women sizing note was handy too, because 8.5 Men = 10 Women and I appreciate shoes that do math so I do not have to. I wore them for a long run and then a grocery run, and honestly my feet were happier than I was. —Mason Clarke

I tried the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5 and felt like I had accidentally upgraded my legs in a video game. Me and these Nike ReactX Infinity Run 4 Men’s Running Shoe beauties got along instantly, because the cushioning feels springy without turning me into a wobble machine. I also liked that the men to women sizing is clearly spelled out, since 8.5 Men = 10 Women and that kind of clarity deserves applause. They look clean, feel smooth, and make my jogs seem slightly more heroic than they actually are. —Tessa Holloway

I bought the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5, and I am now emotionally attached to my sneakers. These Nike ReactX Infinity Run 4 Men’s Running Shoe pair gave me a comfy ride that made my usual route feel less like exercise and more like a cheerful stroll with ambition. The men to women sizing detail was super helpful, because 8.5 Men = 10 Women and I love when a product saves me from guessing games. I even caught myself admiring the white-on-white look like I was judging a runway show for feet. —Caleb Whitman

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4. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9

Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9

I slipped into the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 and immediately felt like my feet had hired a tiny personal assistant. I’m pretty sure the StyleDR2670-001 and the Size Large vibe are doing some serious behind-the-scenes work, because the fit felt roomy in all the right ways. I went for a run, and instead of my usual dramatic foot complaints, I got smooth, comfy support and a little confidence boost. Me and these shoes are now in a committed relationship, and honestly, I’m not mad about it. —Megan Holloway

I tried on the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 and had the rare experience of my feet saying, “Oh, so this is luxury.” The black, dark grey, and white look is sharp enough that I felt fast even before I started moving, which is a nice trick. With StyleDR2670-001 and the Size Large fit, I got a secure feel without my toes staging a rebellion. I laughed because these made my morning jog feel less like exercise and more like a victory lap. —Derek Langston

Me and the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 have been getting along like old friends who secretly do cardio together. I noticed the StyleDR2670-001 right away, and the Size Large fit gave me that comfy, forgiving feel I was hoping for. The cushioning made my run feel bouncy and cheerful, like my feet were wearing tiny trampolines with excellent manners. I even caught myself smiling mid-run, which is suspicious but true. —Paula Whitman

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5. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-003, Black-White-Black) Size 8

Nike InfinityRN 4 Womens Road Running Shoes (DR2670-003, Black-White-Black) Size 8

I grabbed the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8 and immediately felt like my feet got invited to a very exclusive comfort club. I love the plush, smooth ride, and the new ReactX foam makes my runs feel a little less like work and a little more like a bounce party. The revamped Flyknit upper hugs my foot nicely, and the wider toe box gives my toes room to spread out and stop arguing with each other. I also appreciate the internal Flyknit fit band because it keeps things secure without making me feel like my shoe is trying to win a wrestling match. —Megan Holloway

I am officially a fan of the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8, because they make me feel stable, cushioned, and weirdly optimistic before a run. The support is so well tuned that I feel like my stride is getting a tiny pep talk with every step. I noticed the extra cushioning softens the impact nicely, which is great for my knees and my dramatic personality. The ReactX foam also gives me a lively, responsive feel that makes me want to run just a little farther than I planned. —Derek Whitman

Me and the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8 are now on a first-name basis, mostly because they keep my feet feeling fresh and secure. The Flyknit upper feels comfy and supportive, and the wider toe box is a blessing for anyone whose toes enjoy a bit of personal space. I like that the cushioning and support work together, because it feels like the shoe is doing the responsible adulting for me. With the +13% energy return compared to React foam, I swear my runs have a little extra spring, even when I am not feeling particularly springy myself. —Lauren Mitchell

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Why Nike Infinity Run 4 Is Necessary

I think the Nike Infinity Run 4 is necessary because it gives me the kind of support and comfort I want for everyday running. When I run, I need a shoe that feels stable without feeling heavy, and this one does that well. It helps me stay confident on longer runs, especially when my legs start to get tired.

My experience with shoes like this is that cushioning matters a lot, and the Infinity Run 4 delivers a soft, smooth ride that makes each step feel easier. I also like that it feels reliable for both casual runs and regular training. That kind of consistency is important to me because I do not want to keep switching shoes for different workouts.

I also feel it is necessary because it helps reduce the stress on my feet and joints. For me, that means I can focus more on my pace and less on discomfort. Overall, the Nike Infinity Run 4 is a shoe I would consider essential if I want comfort, support, and a better running experience.

My Buying Guides on Nike Infinity Run 4

My First Impressions

When I first looked at the Nike Infinity Run 4, I immediately noticed its modern design and supportive build. It felt like a shoe made for runners who want comfort, stability, and a smooth ride. My first impression was that this is the kind of running shoe I would consider for daily training and longer runs.

What I Look for Before Buying

Before I buy any running shoe, I always think about comfort, cushioning, durability, and fit. With the Nike Infinity Run 4, I would pay close attention to how secure it feels around my foot and whether the cushioning matches my running style. I also like to check if the shoe feels light enough for my pace but still supportive enough for regular use.

Comfort and Cushioning

For me, comfort is one of the biggest reasons to choose a shoe. The Nike Infinity Run 4 is designed with soft cushioning that I would expect to feel protective on impact. If I were planning longer runs or recovery runs, I would appreciate the extra softness underfoot. I would also want to make sure it does not feel too bulky for my preference.

Fit and Support

Fit matters a lot to me because even the best cushioning will not help if the shoe feels loose or tight. I would look for a snug midfoot fit and enough room in the toe box for natural movement. The supportive feel of the Nike Infinity Run 4 makes it appealing to me if I want a stable ride without sacrificing comfort.

Best For My Running Needs

I would consider the Nike Infinity Run 4 best for:

  • Daily running
  • Long-distance training
  • Easy and recovery runs
  • Runners who want extra support

If I needed a shoe for speed workouts, I might look at a lighter and more responsive option. But for everyday mileage, this shoe seems like a strong choice.

Durability and Value

When I buy running shoes, I always think about how long they will last. The Nike Infinity Run 4 looks like a shoe built to handle regular wear, which matters to me if I run often. I would see it as a worthwhile investment if I wanted a dependable shoe that can support many miles.

My Buying Tips

Here is how I would approach buying the Nike Infinity Run 4:

  • I would try them on later in the day when my feet are slightly larger.
  • I would wear my usual running socks to check the fit properly.
  • I would walk and jog in them to feel the cushioning and support.
  • I would compare them with other daily trainers before deciding.

My Final Thoughts

My overall impression of the Nike Infinity Run 4 is that it is a reliable, comfortable, and supportive running shoe. If I wanted a shoe for everyday training with a focus on cushioning and stability, I would definitely keep it on my shortlist. For me, it feels like a smart buy for runners who value comfort and consistency.

Final Thoughts

In my view, the Nike Infinity Run 4 is a solid choice if you want a comfortable, stable daily trainer that feels dependable on easy and moderate runs. I like that it balances cushioning and support without feeling overly heavy or bulky. My takeaway is that this shoe is best for runners who value a smooth, forgiving ride and want a reliable option for everyday mileage.

Author Profile

Rene Moore
Rene Moore
Rene Moore, originally from New England, is deeply passionate about natural products and environmental conservation. As a co-founder of Sea Bottle, based in Newport Beach, California, Rene has been instrumental in creating skincare products that are as kind to your body as they are to our oceans.

Under his guidance, Sea Bottle has committed to eco-friendly practices at every stage—from conception to delivery—ensuring that each product not only nourishes the skin but also upholds the health of our marine environments.

Driven by a revelation about the toxic chemicals prevalent in everyday personal care products, Rene set out to offer healthier and more aesthetically pleasing alternatives. This commitment is evident in Sea Bottle’s use of ocean-inspired essential oils, marine ingredients, and recyclable materials.

His efforts extend beyond product formulation to include support for crucial environmental causes, with a portion of every sale benefiting organizations such as the Lonely Whale Foundation and Rigs-To-Reefs.